原著論文
1. full text links
full text provider logo
actions
Cite
Favorites
share
page navigation
Title & authors
Abstract
Conflict of interest statement
Figures
Similar articles
References
Related information
LinkOut – more resources
原著
1.Mine K, Nagafuchi S, Anzai K, et al. Tyk2-mediated signaling promotes the development of
autoreactive CD8+ CTLs in type 1 diabetes. Nat Commun 15(1):1337, 2024.
2.Jimbo E, Kobayashi T, Mine K, Nagafuchi S, Anzai K, et al. Immunohistochemical detection of
enteroviruses in pancreatic tissue of patients with type 1 diabetes using a polyclonal antibody
against 2A protease of coxsackievirus. J Diabetes Investig 13(3):435-442, 2022.
3. Mori H, Takahashi H, Mine K, Higashimoto K, Inoue K, Kojima M, Kuroki S, Eguchi T, Ono Y, Inuzuka S, Soejima H, Nagafuchi S, Anzai K. TYK2 promoter variant is associated with impaired insulin secretion and lower insulin resistance in Japanese yype 2 diabetes patients. Genes 12:400, 2021.DOI:10.3390/genes12030400.
4.Mine K, Nagafuchi S, Hatano S, Tanaka K, Mori H, Takahashi H, Anzai K, Yoshikai Y. Impaired Upregulation of Stat2 Gene Restrictive to Pancreatic β-cells is Responsible for Virus-Induced Diabetes in DBA/2 Mice. BBRC 521:853-860, 2020. DOI:10.1016/j.bbrc.2019.10.193.
5. Mine K, Hirakawa K, Kondo S, Minami M, Okada A, Tsutsu N, Yokogawa Y, Hibio Y, Kojima F, Fujimoto S, Kurisaki H, Anzai K, Yoshikai Y, Nagafuchi S. Subtyping of type 1 diabetes as classified by anti-GAD antiboy, IgE levels, and tyrosin kinase 2 (TYK2) promoter variant in the Japanese. EBioMedicine 23:46-51, 2017. DOI:10.1016/j.ebiom.2017.08.012
6. Izumi K, Mine K, Inoue Y, Teshima M, Ogawa S, Kai Y, Kurafuji T, Hirakawa K, Miyakawa D, Ikeda H, Inada A, Hara M, Yamada H, Akashi K, Niho Y, Ina K, Kobayashi T, Yoshikai Y, Anzai K, Yamashita T, Minagawa H, Fujimoto S, Kurisaki H, Shimoda K, Katsuta H, Nagafuchi S. Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes.Nat Commun 6:e6748, 2015. DOI:10.1038/ncomms774
7. Nagafuchi S, KamadaY, Hirakawa K, Tsutsu N, Minami M, Okada A, Kai K, Teshima M, Moroishi A, Murakami Y, Umeno Y,Yokogawa Y, Kogawa K, Izumi K, Anzai K, Iwakiri R, Hamaguchi K, Sasaki N, Nohara S, Yoshida E, Harada M, Akashi K, Yanase T, Ono J, Okeda T, Fujimoto R,Ihara K, Hara T, Kikuchi Y, Iwase M, Kitazono T, Kojima F, Kono S, Kurisaki H, Kondo S, Katsuta H. TYK2 promoter variant and diabetes mellitus in the Japanese. EBioMedicine i2:744-749, 2015. DOI:10.1016/j.ebiom.2015.00
8. Kounoue E, Izumi K,Ogawa S, Kondo S,Katsuta H, Akashi T,Niho Y, Harada M, Tamiya S, Kurisaki H, NagafuchiS. The significance of T cells, B cells, antibodies and macrophages against encephalomyocarditis (EMC)-D virus-induced diabetes in mice. Arch Virol 153:1223-1231, 2008
9. Kounoue E, Nagafuchi S, Nakamura M, Nakano S, Koga T, Nakayama M, Mituyama M, Niho Y, Takaki R. Encephalomyocarditis (EMC) virus-induced diabetes mellitus prevented by Corynebacterium parvum in mice. Experientia 43 : 430-431, 1987
総説
1. Nagafuchi S. Regulation of Viral Infection in Diabetes. (as Guest Editor of Biology 10(6) issue) Biology 10(6):529, 2021.
2. Mine K, Yoshikai Y, Takahashi H, Mori H, Anzai K, Nagafuchi S. Genetic susceptibility of the host in virus-induced diabetes. Microorganisms 8(8):1133, 2020.
2. Nagafuchi S, Mine K, Takahashi H, Yoshikai Y, Anzai K. Viruses with masked pathogenicity and genetically susceptible hosts-How to discover potentially pathogenic viruses. (Commentary)(With Front Cover)
Journal of Medical Virology. 91:1365-1367, 2019. (with Front Cover)
2. Mine K, Takahashi H, Nagafuchi S. Model Animal Mimicking Human Virus-induced Diabetes.
EBioMedicine. (32), 8. 2018.
2.永淵正法、三根敬一朗、吉開泰信. ウイルス糖尿病の疾患感受性遺伝子.
新時代の臨床糖尿病学（上）増刊号. p.212-217, 日本臨牀, 2018.
3. 永淵正法、勝田仁、三根敬一朗、吉開泰信. ウイルスによる膵島細胞傷害-ウイルス糖尿病予防ワクチン開発 は可能か- 実験医学増刊号 糖尿病研究の“いま”と“これから”（羊土社） 35:40-46, 2017.
4. 永淵正法、三根敬一朗、栗崎宏憲、勝田仁. ウイルス糖尿病感受性遺伝子の発見と、これからの展開.
糖尿病学 門脇孝編 p.1-11. 診断と治療社 2016.
5. 永淵正法. ウイルス感染・１型糖尿病発症制御機構の解明と、これからの展開.
福岡医学雑誌 107:105-114, 2016.
6. 永淵正法、安西慶三. ウイルスと1型糖尿病.
Diabetes Frontier 27:759-766, 2016.
7. Nagafuchi S. Virus-induced diabetes: Koch’s Postulate fulfillable?
Int J Diabetes Clin Diagn 3:115, 2016. doi.org/10.15344/2394-1499/2016/11
8 Nagafuchi S. Zika virus infection in SJL mice: Tyk2 gene deficiency.
Web comments on Nature 534:267-271, 2016
9. Nagafuchi S, Toniolo A, Viral Diabetes: Virus diabetogenicity and host susceptibility.
Immunoendocrinology 2:e1026, 2015.
10. 永淵正法、大澤進、和泉賢一、小川秀一郎、栗崎宏憲、高上悦志. 1型糖尿病の成因③環境因子.Diabetes Frontier 19(2):180-184, 2008.
11. 永淵正法、小川秀一郎、栗崎宏憲. エンテロウイルス感染症と臓器障害のメカニズム —膵島障害と糖尿病誘発—. 臨床とウイルス 35(3): 146-151, 2007.
その他の研究成果については下記PDFをご覧ください
